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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADD2
All Species:
22.73
Human Site:
T688
Identified Species:
55.56
UniProt:
P35612
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35612
NP_001608.1
726
80854
T688
K
D
K
T
E
S
V
T
S
G
P
M
S
P
E
Chimpanzee
Pan troglodytes
XP_001143122
726
80832
T688
K
D
K
T
E
S
V
T
S
G
P
M
S
P
E
Rhesus Macaque
Macaca mulatta
XP_001100191
726
80838
T688
K
D
K
T
E
S
V
T
S
G
P
M
S
P
E
Dog
Lupus familis
XP_853066
722
79644
T684
K
D
K
T
E
S
V
T
S
G
P
M
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYB8
725
80623
T687
K
D
K
T
E
S
V
T
S
G
P
L
S
P
E
Rat
Rattus norvegicus
Q05764
725
80574
T687
K
D
K
T
E
S
V
T
S
G
P
L
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512778
707
79109
I669
T
I
K
S
S
E
K
I
E
E
V
L
S
P
E
Chicken
Gallus gallus
NP_989434
709
78787
I671
T
I
K
S
S
E
K
I
E
E
A
L
S
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02645
1156
127921
P1077
V
H
R
S
N
S
A
P
E
L
C
H
T
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U9K0
732
82151
K682
T
E
Y
P
E
K
V
K
M
T
R
F
S
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
92.1
N.A.
92.5
92.1
N.A.
54.9
56.3
N.A.
N.A.
N.A.
25.2
N.A.
27.4
N.A.
Protein Similarity:
100
99.8
99.8
95.4
N.A.
95.4
94.7
N.A.
74.5
73.4
N.A.
N.A.
N.A.
41.7
N.A.
50.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
26.6
N.A.
N.A.
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
40
N.A.
N.A.
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
70
20
0
0
30
20
0
0
0
0
80
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
20
0
0
0
0
0
0
0
% I
% Lys:
60
0
80
0
0
10
20
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
40
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
40
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
60
0
0
80
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
30
20
70
0
0
60
0
0
0
90
10
10
% S
% Thr:
30
0
0
60
0
0
0
60
0
10
0
0
10
0
10
% T
% Val:
10
0
0
0
0
0
70
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _